Sexually Transmitted Diseases (STDs)

The following information is courtesy of the CDC. This information focuses primarily on Chlamydia, gonorrhea, and syphilis.  At the bottom of the page is more information about other sexually transmitted diseases. 

Chlamydia: Expanded Screening Efforts Result in More Reported Cases, But Majority of Infections Remain Undiagnosed

Chlamydia remains the most commonly reported infectious disease in the United States. In 2004, 929,462 chlamydia diagnoses were reported, up from 877,478 in 2003. Even so, most chlamydia cases go undiagnosed. It is estimated that there are approximately 2.8 million new cases of chlamydia in the United States each year.1

The national rate of reported chlamydia in 2004 was 319.6 cases per 100,000 population, an increase of 5.9 percent from 2003 (301.7). The increases in reported cases and rates likely reflect the continued expansion of screening efforts and increased use of more sensitive diagnostic tests, rather than an actual increase in new infections.

Impact on Women

Female Chlamydia Rates, 2004Women, especially young women, are hit hardest by chlamydia. Studies have found that chlamydia is more common among young women than young men, and the long-term consequences of untreated disease for women are much more severe. The chlamydia case rate for females in 2004 was 3.3 times higher than for males (485.0 vs. 147.1). However, much of this difference reflects the fact that women are far more likely to be screened than men. Females ages 15 to 19 had the highest chlamydia rate (2,761.5), followed by females ages 20 to 24 (2,630.7).

African-American women are also disproportionately impacted by chlamydia. In 2004, the rate of reported chlamydia among black females (1,722.3) was more than 7.5 times that of white females (226.6). Because case reports do not provide a complete account of the burden of disease, researchers also evaluate chlamydia prevalence in subgroups of the population to better estimate the true extent of the disease. For example, data from chlamydia screening in family planning clinics across the United States indicates that roughly 6 percent of 15- to 24-year-old females in these settings are infected.

Importance of Screening

Because chlamydia is most common among young women, CDC recommends annual chlamydia screening for sexually active women under age 26, as well as older women with risk factors such as new or multiple sex partners.5 Data from a study in a managed care setting suggest that chlamydia screening and treatment can reduce incidence of PID by over 50 percent.6 Unfortunately, many sexually active young women are not being tested for chlamydia, in part reflecting a lack of awareness among some providers and limited resources for screening.5,7 Recent research has shown that a simple change in clinical procedures — coupling chlamydia tests with routine Pap testing — can sharply increase the proportion of sexually active young women screened.8 Stepping up screening efforts is critical to preventing the serious health consequences of this infection, particularly infertility.

While screening is critical for sexually active young women, improved testing and treatment among men could help reduce transmission to women. The availability of urine tests for chlamydia may be contributing to increased detection of the disease in men, and consequently the rising rates of reported chlamydia in men in recent years (from 99.6 in 2000 to 147.1 in 2004).

Health Consequences of Chlamydia

Chlamydia is a bacterial infection that can easily be cured with antibiotics, but it is usually asymptomatic and often undiagnosed. Untreated, it can cause severe health consequences for women, including pelvic inflammatory disease (PID), ectopic pregnancy, and infertility. Up to 40 percent of females with untreated chlamydia infections develop PID, and 20 percent of those may become infertile.3 In addition, women infected with chlamydia are up to five times more likely to become infected with HIV, if exposed.4 Complications from chlamydia among men are relatively uncommon, but may include epididymitis and urethritis, which can cause pain, fever, and in rare cases, sterility.

Chlamydia Statistics

Although chlamydia in women is a widely distributed STD among all racial and ethnic groups, trends in positivity in women screened in HHS Region X show consistently higher chlamydia positivity among minorities (Figure P).

In 2004, the rate of chlamydia among African-American females in the United States was more than 7 times higher than the rate among white females (1,722.3 and 226.6 per 100,000, respectively) (Table 11B). The chlamydia rate among African-American males was more than 11 times higher than that among white males (645.2 and 57.3 per 100,000 population, respectively).

Chlamydia - Positivity among women tested in family planning clinics by race and ethnicity: Region X, 1988-2004

Figure P. Chlamydia - Positivity among women tested in family planning clinics by race and ethnicity: Region X, 1988-2004
Note: Women who met screening criteria were tested. Annual race/ethnicity-specific positivity not adjusted for changes in laboratory test method and associated increases in test sensitivity in 1994, and 1999-2004.
SOURCE: Regional Infertility Prevention Projects: Region X Chlamydia Project


Gonorrhea: Disease Rate Falls to Historic Low But Drug Resistance on the Rise

Gonorrhea is the second most commonly reported infectious disease in the United States, with 330,132 cases reported in 2004. From a high of 467.7 cases per 100,000 population reported in 1975, the U.S. gonorrhea rate fell to 113.5 in 2004 (a 76% decline) — the lowest recorded level since reporting began in 1941. More recently, from 2003 to 2004, the rate fell 1.5 percent (from 115.2 cases per 100,000 population to 113.5). Like chlamydia, however, gonorrhea is substantially under diagnosed and under reported, and approximately twice as many new infections are estimated to occur each year as are reported.1

Gonorrhea Rate, 1941-2004

Racial Disparities Persist

African Americans remain the group most heavily affected by gonorrhea. While the rate of gonorrhea among blacks fell 3.0 percent from 2003 to 2004, the reported 2004 rate per 100,000 population for blacks (629.6) was 19 times greater than for whites (33.3). In 2003, the rate for blacks was 20 times higher than the rate for whites.

American Indians/Alaska Natives had the second-highest gonorrhea rate in 2004 (117.7, up 14.8% from 2003), followed by Hispanics (71.3, up 2.3% from 2003), whites (33.3, up 2.1% from 2003), and Asians/Pacific Islanders (21.4, down 3.2% from 2003).

Ethnic minorities in the United States have traditionally had higher rates of reported gonorrhea and other STDs, in part a reflection of limited access to quality health care, poverty, and higher background prevalence of disease in these populations.

Drug Resistance Increasing In Communities Across the United States

Drug resistance is an increasingly important concern in the treatment and prevention of gonorrhea.10 CDC monitors trends in gonorrhea drug resistance through the Gonococcal Isolate Surveillance Project (GISP), which tests gonorrhea samples (“isolates”) from the first 25 men with urethral gonorrhea attending STD clinics each month in sentinel clinics across the United States (28 cities in 2004).11

Overall, 6.8 percent of gonorrhea isolates tested through GISP in 2004 demonstrated resistance to fluoroquinolones, a leading class of antibiotics used to treat the disease, compared to 4.1 percent in 2003 and 2.2 percent in 2002. Resistance is especially worrisome among men who have sex with men (MSM), where resistance was eight times higher than among heterosexuals (23.8% vs. 2.9%).

In April 2004, CDC recommended that fluoroquinolones no longer be used as treatment for gonorrhea among MSM. Fluoroquinolones are also not recommended to treat gonorrhea in anyone in California and Hawaii, where fluoroquinolone-resistant cases have been widespread for several years. Outside of these states in 2004, 17.8 percent of gonorrhea isolates among MSM were resistant to fluoroquinolones, while resistance among heterosexuals remained low at 1.3 percent.

Health Consequences of Gonorrhea

While gonorrhea is easily cured, untreated cases can lead to serious health problems. Among women, gonorrhea is a major cause of PID, which can lead to chronic pelvic pain, ectopic pregnancy, and infertility. In men, untreated gonorrhea can cause epididymitis, a painful condition of the testicles that can result in infertility. In addition, studies suggest that presence of gonorrhea infection makes an individual three to five times more likely to acquire HIV, if exposed.9

Gonorrhea Statistics

In 2004, 69.6% of the total number of cases of gonorrhea reported to CDC occurred among African-Americans (Table 21A). In 2004, the rate of gonorrhea among African-Americans was 629.6 cases per 100,000 population, among American Indian/Alaska Natives the rate was 117.7, and among Hispanics the rate was 71.3. These rates are 19, 4, and 2 times higher, respectively, than the rate among whites in 2004 of 33.3 cases per 100,000 population. The rate of gonorrhea among Asian/Pacific Islanders in 2004 was 21.4 cases per 100,000 population (Figure 15, Table 21B).

From 2000 through 2004, gonorrhea rates among African-Americans declined by 19.1% (778.1 and 629.6 cases per 100,000 population, respectively). During the same period, gonorrhea rates increased by 19.8% among whites, 19.4% among American Indian/Alaska Natives, and 3.8% among Hispanics, and decreased by 19.9% among Asian/Pacific Islanders (Table 21B).

Gonorrhea rates in 2004 among African-American men were 26 times higher than among white men. Gonorrhea rates in 2004 among African-American women were 15 times higher than among white women (Figure Q).

Gonorrhea rates in 2004 were highest for African-Americans aged 15-24 years among all racial, ethnic, and age categories. In 2004, African-American women aged 15-19 years had a gonorrhea rate of 2,790.5 cases per 100,000 females. This rate was 14 times greater than the 2004 rate among white females of similar age (201.7). African-American men in the 15- to 19-year-old age category had a 2004 gonorrhea rate of 1,390.1 cases per 100,000 males, which was 37 times higher than the rate among 15- to 19-year-old white males of 37.9 per 100,000. Among 20- to 24-year-olds in 2004, the gonorrhea rate among African-Americans was 17 times greater than that among whites (2,487.2 and 149.0 cases per 100,000 population, respectively) (Table 21B).

Although gonorrhea rates decreased for most age and race/ethnic groups during the 1980s, they did not decrease for African-American adolescents during this period; African-American 15- to 19-year-old females did not show a decrease in rates until 1991 (Figure R). Decreases among 15- to 19-year old African-American males did not begin until 1992 (Figure S). From 2000 to 2004, gonorrhea rates among 15- to 19-year-old African-American females and males decreased 19.7% and 25.5%, respectively.

Gonorrhea - Rates by race/ethnicity and sex, 2004

Figure Q. Gonorrhea - Rates by race/ethnicity and sex, 2004

Gonorrhea - Rates among 15- to 19-year-old females by race and ethnicity: United States, 1981-2004

Figure R. Gonorrhea - Rates among 15- to 19-year-old females by race and ethnicity: United States, 1981-2004

Gonorrhea - Rates among 15- to 19-year-old males by race and ethnicity: United States, 1981-2004

Figure S. Gonorrhea - Rates among 15- to 19-year-old males by race and ethnicity: United States, 1981-2004

 

Syphilis: Cases Increase for Fourth
Consecutive Year

The rate of primary and secondary (P&S) syphilis — the most infectious stages of the disease — decreased throughout the 1990s, and in 2000 reached an all-time low. However, over the past four years the syphilis rate in the United States has been increasing. Between 2003 and 2004 alone, the national P&S syphilis rate increased 8 percent, from 2.5 to 2.7 cases per 100,000 population; during this time, reported P&S cases in the United States increased from 7,177 to 7,980.

Overall, increases in P&S syphilis rates between 2000 and 2004 were observed only among men. The rate of P&S syphilis among males rose 81 percent between 2000 and 2004 (from 2.6 to 4.7), and 11.9 percent between 2003 (4.2) and 2004. Notably, in 2004 — for the first time in over 10 years — the rate among females did not decrease, remaining at 0.8. Between 2003 and 2004, the rate of congenital syphilis (i.e., transmission from mother to child) decreased 17.8 percent (from 10.7 to 8.8 per 100,000 live births), likely reflecting the substantial reduction in syphilis among women that has occurred over the past decade.

P&S Syphilis Rates By Sex, 1981-2004

Rising Rate Driven By Cases Among Men

Estimated P&S Syphilis Cases, 2004 - Transmission CategoryIncreasing cases of P&S syphilis among MSM are believed to be largely responsible for the overall increases in the national syphilis rate observed since 2000. Until very recently, CDC has not collected data by risk group. However, the male-to-female ratio for P&S syphilis has risen steadily between 2000 and 2004 (from 1.5 to 5.9), suggesting increased syphilis transmission among MSM. This increase occurred among all racial and ethnic groups. Additionally, CDC estimates that MSM comprised 64 percent of P&S syphilis cases in 2004, up from 5 percent in 1999.12
 

Recent Declines Among African Americans Possibly Reversing

In 2004, the P&S syphilis rate among blacks increased for the first time in more than a decade — 16.9 percent from 2003 to 2004 (from 7.7 to 9.0), with the most significant increases among black men. Between 2003 and 2004, the syphilis rate among black males increased 22.6 percent (from 11.5 to 14.1), while the rate among black women rose 2.4 percent (from 4.2 to 4.3). In addition, the male-to-female ratio for blacks rose from 2.7 in 2003 to 3.3 in 2004, suggesting increases among black MSM.

Racial gaps in syphilis rates are narrowing, with rates in 2004 5.6 times higher among blacks than among whites, a substantially lower differential than in 2000, when the rate among blacks was 24 times greater than among whites. This narrowing reflects both declining disease rates among African Americans and the significant increases among white men in recent years. Continued progress in eliminating this disease will require an ongoing commitment to syphilis education, testing, and treatment in all populations affected.

Urban Areas Bear Greatest Syphilis Burden

Syphilis remains a public health problem in metropolitan areas with large populations of MSM. For the third consecutive year, San Francisco had the highest P&S rate of any U.S. city in 2004 (45.9). Other leading cities include Atlanta, Georgia (34.6); Baltimore, Maryland (33.2); New Orleans, Louisiana (16.4); St Louis, Missouri (14.1); Detroit, Michigan (13.5); Washington, D.C. (12.2); Dallas, Texas (11.6); Jersey City, New Jersey (10.8); and Chicago, Illinois (9.7).

Health Consequences of Syphilis

Syphilis, a genital ulcerative disease, is highly infectious, but easily curable in its early (primary and secondary) stages. If untreated, it can lead to serious long-term complications, including nerve, cardiovascular, and organ damage, and even death. Congenital syphilis can cause stillbirth, death soon after birth, and physical deformity and neurological complications in children who survive. Syphilis, like many other STDs, facilitates the spread of HIV, increasing transmission of the virus at least two- to five-fold.13

Cities with Highest Reported Rates of P&S Syphilis, 2004
 Cities with Highest Reported Rates of P&S Syphilis, 2004

Primary and Secondary Syphilis Statistics

The syphilis epidemic in the late 1980s occurred primarily among heterosexual, minority populations.1 During the 1990s, the rate of primary and secondary (P&S) syphilis declined among all racial and ethnic groups (Figure 31). During 2000-2004, the rate continued to decline among African-Americans, but the overall rate of P&S syphilis and rates among non-Hispanic whites, Hispanics, Asian/Pacific Islanders, and American Indian/Alaska Natives increased; increases in P&S syphilis occurred only among men and the most rapid rate of increase occurred among non-Hispanic white men during this time (Table 34B).

Between 2003 and 2004, the rates of primary and secondary syphilis increased 11% in white men, 17% in African-American men and increased slightly (2%) among African-American women (Table 34B). Rates continued to increase among Hispanics, Asian/Pacific Islanders, and American Indian/Alaska Natives.

In 2004, 41% of all cases of P&S syphilis reported to CDC occurred among African-Americans and 40% of all cases occurred among non-Hispanic whites (Table 34A). The 2004 rate for African-Americans was 6 times greater than the rate among non-Hispanic whites (Table 34B).

In 2004, the incidence of P&S syphilis by sex among African-Americans was highest among women aged 20-24 years (13.4 cases per 100,000 population) and among men aged 25-29 (34.6 cases per 100,000 population) (Table 34B). In 2003, African-American men in the 35-39 age group had the highest rates.

Between 2003 and 2004, P&S syphilis rates for African-Americans in every age group increased. (Table 34B).

In 2004, 16% of all cases of P&S syphilis reported to CDC occurred among Hispanics (Table 34A). The rate of P&S syphilis among Hispanic men increased 12% (from 4.9 to 5.5 cases per 100,000 population) between 2003 and 2004. The rate among Hispanic women remained essentially unchanged (0.7 cases per 100,000 population). The rate among Hispanics in 2004 was 2 times greater than the rate among non-Hispanic whites.

The incidence of P&S syphilis among Hispanics was highest among women aged 20-24 years (1.9 cases per 100,000 population) and among men aged 35-39 years (14.0 cases per 100,000 population) in 2004 (Table 34B).

Congenital Syphilis Statistics

In 2004, the rate of congenital syphilis (based on the mother's race/ethnicity) was 26.7 cases per 100,000 live births among African-Americans and 16.2 cases per 100,000 live births among Hispanics. These rates are 16 and 10 times greater, respectively, than the 2004 rate among non-Hispanic whites (1.7 cases per 100,000 live births), respectively (Figure W, Table 44).

 

Below are several of the most commonly asked about sexually transmitted diseases. Click on each for more information.

Bacterial Vaginosis
Chlamydia
Genital HPV Infection
Genital Herpes
Gonorrhea
Antibiotic Resistant Gonorrhea
Pelvic Inflammatory Disease
STD Detection and Treatment in HIV Prevention
STDs and Pregnancy
Syphilis
Syphilis and Men who have sex with men
Trichomoniasis
 

For more information:

Centers for Disease Control and Prevention

The CDC has several web pages with helpful information about the prevention of sexually transmitted diseases.  This includes the 2004 Surveillance Report which has statistics

California DHS STD Control Branch Publications

This website offers up-to-date California STD morbidity data, surveillance reports, California Lab Survey, and California STD treatment guides.
 

>HIV/AIDS RESOURCES HOMEPAGE<


228 S. Muskogee Avenue   Tahlequah, OK 74464
Telephone: 918-456-6094   Fax: 918-456-8128   Email: peiron@niwhrc.org